Ouyang Ying Bun: I am very fortunate to early 2012, I joined the game industry (Guangzhou) biotechn

Biological exploration: Dr. Ouyang Hello, you're an international leading experts in the field of genetic sea glass wreath engineering animal models, and we can share your work experience abroad before it?
Should Ouyang Bin: Military Medical Academy after I received his PhD in molecular genetics, 1995 to Indiana University sea glass wreath and the United States during the Oklahoma Medical Research sea glass wreath Foundation postdoctoral student, trained in molecular genetics in mice, while contact with the gene Target training techniques, and in this period successfully established an animal model of three gene knockout mice, from 2002 began to enter the industry, beginning in 2004, joined New Jersey in the U.S. biotechnology company Taconic, Taconic are the three U.S. model animal suppliers. As part of the person in charge of the design of molecular biology, I am responsible for genetically engineered mice model strategy, project management, staff recruitment and training, project follow-up, customer service, and so on. Between Taconic7 years, this demand is constantly increasing, our size has gradually expanded to 2011, annually provides hundreds of genes in animal models, the output can reach tens of millions of dollars.
Ouyang Ying Bun: I am very fortunate to early 2012, I joined the game industry (Guangzhou) biotechnology company, is the largest game industry genetically engineered animal models of commercial suppliers. I joined the game industry is the main reason I am very optimistic sea glass wreath about the prospects Cyagen future development. Although these years our country very fast development of biotechnology, the state invested in this area is very large, but our country's lack of independent biological reagents, bio-services brand. The vast majority of funds are flowing to foreign agents and suppliers there, which greatly limits the development of domestic biotechnology. Competition in the domestic industry, the reagent has done a very good attempt, I think in this regard after some of the big.
Ouyang Ying Bun: Race industry has built a very large business platform genetically sea glass wreath engineered animal models, I was mainly responsible for the optimization platform, how to be more effective operating platform, making the generation of animal models of genetic sea glass wreath engineering process more efficient. In the shortest possible time to provide the best service. In addition to these transgenic animals and gene targeting technology beyond the past two years with the development sea glass wreath of ZFN and TALEN and other new technologies, the scope of genetic engineering of animals is increasing, then ZFN and TALEN and other new technologies enable us in a very short time the obtained gene targeting and gene knockout animal models. sea glass wreath And it is not limited to mice, rats can be extended to the technical body, so now game industry has completely mastered the ZFN and TALEN technology is making these processes to optimize and promote these technologies. sea glass wreath So I am currently working in the game industry are mainly of two parts, and a new platform to optimize existing technology introduction.
Ouyang Ying-bin: the early years, we were doing when the Human Genome Project, when people are very optimistic, we think the completion of the Human Genome Project, the entire gene sequence of the human figure, and be able to know the mysteries of life. Now it seems, was too optimistic. Even if we know all the sequences of human, but these sequences encoding function is not known. In the post-genomic era, more and more we need to have an appropriate animal model to study gene function, and how they cooperate with each other in the body. We urgently need a suitable animal model. So mouse model of human genes are actually the best model, why do you say that with the completion of the sequence of the human genome project and mice, although the difference between human and mouse is very large, at the genetic level and the level of DNA On both of them are very similar. Almost all genes can be found in the corresponding gene in mice, the mice have almost all physiological systems, so that the mouse is very good as a research animal models of human genes. Especially in the early 1980s, when, with the development of molecular biology, scientists discovered prokaryotic injection method can be used, the exogenous gene can be very effectively introduced into the mouse genome, which made transgenic mice, so we can study gene expression in vivo after what effect, in the late 1980s to the 1990s, with the development of mouse embryonic stem cell technology and homologous recombination technology, allows us to be able to carry out a modification of a gene in mice, for example, by homologous recombination technology to knock it away, and this is a very useful technique, then we can get rid of the mice after knockout mice have any change, which is the study of mouse gene is very effective tool. It can be said transgenic technology sea glass wreath and gene targeting technology, and the same PCR technique is a milestone in the development of molecular biology. One step closer to the 1990s, the development of second-generation targeting sea glass wreath technology, which is conditional gene knockout technology, is at a particular time, a particular organ of the genetic modification, which makes our ability to study greatly improved.
Ouyang Ying Bin: Cyagen Bio 2006 in Guangzhou, which was founded in transgenic animals and gene targeting has done a lot of work so far has built the largest sea glass wreath genetically engineered animal models of commercial platforms, each year hundreds of genes may provide modified sea glass wreath animal models. A few years ago our major customers sea glass wreath are abroad, including leading universities such as Harvard, Stanford and the like. A professor at Stanford last thirty kinds use animal models we offer, sea glass wreath he used the influence of the transcription sea glass wreath of certain genes in animal model systems of these conditions on aspects of animal evolution, get very beneficial results, published in the Nature article get a lot of attention. I think with our ability Cyagen animal products increasing, the name of our game industry will increasingly appear on the top of the magazine. In recent years, as China's investment in scientific research and further development, sea glass wreath the demand for domestic research institutes and universities, an increasing number of genetic engineering, we now have got a lot of domestic orders. Our production platform mice are increasingly unable to meet our customers' needs, so in 2012 we created a lot of mice in Suzhou production platform, I believe that with the continuous development of our company, our goal is internationally establish a leading position in mice and rats genetically engineered animal platform.